Inhibition of BMPER Mitigates Pulmonary Hypertension by Modulating LRP1-YAP Interaction in Smooth Muscle Cells
Collectively, these results implicate secreted BMPER as a discrete regulator for pulmonary vascular remodeling and suggest its inhibition as a new potential therapeutic strategy against PH.
Authors
- Lavannya M. Pandit (ORCID: https://orcid.org/0000-0001-5071-5184)
- Bing Sun (ORCID: https://orcid.org/0000-0002-0350-5835)
- Howard J. Huang (ORCID: https://orcid.org/0000-0002-3358-6795)
- Christopher Ward (ORCID: https://orcid.org/0000-0002-3445-6327)
- Iván O. Rosas (ORCID: https://orcid.org/0000-0003-4622-618X)
- Harry Karmouty‐Quintana (ORCID: https://orcid.org/0000-0003-4753-9823)
- Claire M. Li
- Alan Waich (ORCID: https://orcid.org/0000-0001-5426-4579)
- Xinchun Pi (ORCID: https://orcid.org/0000-0002-1808-8659)
- Hua Mao (ORCID: https://orcid.org/0009-0006-6068-6528)
- Liang Xie
Institutions
- Houston Methodist (US)
- Michael E. DeBakey VA Medical Center (US)
- Baylor College of Medicine (US)
- Veterans Health Administration (US)
- Methodist Hospital (US)
- The University of Texas Health Science Center (US)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1161/atvbaha.124.322189
- Citations
- 2
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.04