Telomere Length of Peripheral Blood Leukocytes Predicts Disease Severity and Worse Survival in Systemic Sclerosis
Short PBL-TL is associated with pulmonary disease severity and predicts worse SSc clinical outcomes. This study provides rationale to further investigate the role of telomere dysfunction in SSc pathogenesis and validate TL as a prognostic biomarker in SSc.
Authors
- Sarah French (ORCID: https://orcid.org/0000-0003-4211-2628)
- Francesco Boin (ORCID: https://orcid.org/0000-0003-4840-3063)
- Paul J. Wolters (ORCID: https://orcid.org/0000-0002-3108-6164)
- Monica Yang (ORCID: https://orcid.org/0000-0002-2693-3648)
- Michael Wax
- Shuo Liu (ORCID: https://orcid.org/0009-0007-6026-7785)
- Seoyeon Lee (ORCID: https://orcid.org/0000-0003-3158-9666)
Institutions
- Cedars-Sinai Medical Center (US)
- University of California, San Francisco (US)
- University of California System (US)
- Liaoning Provincial People's Hospital (CN)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1002/art.43400
- Citations
- 1
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.47