Comparative Analysis of Cervical Disc Arthroplasty and Anterior Cervical Discectomy and Fusion: Trends, Demographics, and Clinical Outcomes in a Nationwide Inpatient Sample

<b>Introduction:</b> Cervical disc disease is a common cause of disability worldwide. Two surgical options for refractory CDD are anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA). While ACDF is well established, CDA offers motion preservation and has shown promising outcomes. This study compared utilization trends, patient characteristics, and hospitalization outcomes of ACDF and CDA using a large national dataset. <b>Methods:</b> We analyzed patients in the Nationwide Inpatient Sample (2016-2019) undergoing ACDF or CDA, identified using ICD-10 codes. After exclusions, 97,999 patients were included. Propensity score matching yielded 11,415 pairs, enabling balanced comparisons of demographics, comorbidities, complications, length of stay (LOS), and hospital charges. <b>Results:</b> CDA utilization increased during the study period. Compared with ACDF, CDA patients were younger and more likely to have private insurance. Following matching, both groups were demographically similar. CDA was associated with a slightly shorter LOS (1.32 vs. 1.39 days) but significantly higher charges (USD 82,431 vs. USD 58,472). In terms of complications, dysphagia was more frequent after ACDF, whereas cervical spinal cord injury and urinary tract infections were slightly more common after CDA, though rare overall. <b>Conclusions:</b> CDA is increasingly adopted in younger, privately insured patients and demonstrates comparable safety with ACDF. Its advantages include motion preservation, shorter hospitalization, and lower dysphagia rates, though at the expense of higher costs. These findings support the selective use of CDA as a viable alternative to ACDF in appropriately chosen patients.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2025-09-18
DOI
https://doi.org/10.3390/jcm14186559
Primary Topic
Cervical and Thoracic Myelopathy
Type
article
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article

Comparative Analysis of Cervical Disc Arthroplasty and Anterior Cervical Discectomy and Fusion: Trends, Demographics, and Clinical Outcomes in a Nationwide Inpatient Sample

Yaron Berkovich, Amit Keren, Eyal Behrbalk, Assil Mahamid et al.
Journal of Clinical Medicine
Cervical and Thoracic Myelopathy
article

Comparative Analysis of Cervical Disc Arthroplasty and Anterior Cervical Discectomy and Fusion: Trends, Demographics, and Clinical Outcomes in a Nationwide Inpatient Sample

Yaron Berkovich, Amit Keren, Eyal Behrbalk, Assil Mahamid, Ali Yassin, Hadar Gan‐Or, Marah Hodruj, David Fishman, Saleem Samara, David Maman
article en

Abstract

<b>Introduction:</b> Cervical disc disease is a common cause of disability worldwide. Two surgical options for refractory CDD are anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA). While ACDF is well established, CDA offers motion preservation and has shown promising outcomes. This study compared utilization trends, patient characteristics, and hospitalization outcomes of ACDF and CDA using a large national dataset. <b>Methods:</b> We analyzed patients in the Nationwide Inpatient Sample (2016-2019) undergoing ACDF or CDA, identified using ICD-10 codes. After exclusions, 97,999 patients were included. Propensity score matching yielded 11,415 pairs, enabling balanced comparisons of demographics, comorbidities, complications, length of stay (LOS), and hospital charges. <b>Results:</b> CDA utilization increased during the study period. Compared with ACDF, CDA patients were younger and more likely to have private insurance. Following matching, both groups were demographically similar. CDA was associated with a slightly shorter LOS (1.32 vs. 1.39 days) but significantly higher charges (USD 82,431 vs. USD 58,472). In terms of complications, dysphagia was more frequent after ACDF, whereas cervical spinal cord injury and urinary tract infections were slightly more common after CDA, though rare overall. <b>Conclusions:</b> CDA is increasingly adopted in younger, privately insured patients and demonstrates comparable safety with ACDF. Its advantages include motion preservation, shorter hospitalization, and lower dysphagia rates, though at the expense of higher costs. These findings support the selective use of CDA as a viable alternative to ACDF in appropriately chosen patients.

Journal of Clinical MedicineVol. 14(18)
Technion – Israel Institute of Technology (IL), Hillel Yaffe Medical Center (IL), Bnai Zion Medical Center (IL), Carmel Medical Center (IL)
Openalex Percentile: Top 59%
Cervical and Thoracic Myelopathy
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