The association between serum magnesium levels and hypertensive disorders of pregnancy

In this South African cohort, cross-sectional comparisons demonstrate lower serum magnesium at term in normotensive pregnancies and a divergent profile in pre-eclampsia, supporting the hypothesis of altered magnesium regulation in hypertensive disorders of pregnancy. Results represent associations rather than causal effects and motivate future longitudinal research with repeated and intracellular magnesium measurements to clarify temporality and clinical relevance.Contribution: This article adds to the limited literature on Mg dynamics in pregnancy and highlights the need for population-specific strategies to reduce maternal mortality.