Utility of reflex cmv immunohistochemistry in patients with inflammatory bowel disease
While evaluating endoscopic biopsies of patients with inflammatory bowel disease, CMV immunohistochemistry assessment as a reflex test may be considered by the pathologist-even in the absence of identifiable viral cytopathic effects with hematoxylin-eosin- particularly when severe histologic inflammation is present. Although the clinical significance of CMV immunohistochemistry could not be fully determined in this study, this approach may increase the likelihood of detecting CMV infection and, in the appropriate clinical context, could contribute to timely diagnosis and management.
Authors
- Doğu Vurallı Bakkaloğlu (ORCID: https://orcid.org/0000-0002-7671-0100)
- Neslihan Berker (ORCID: https://orcid.org/0000-0002-0949-7944)
- Aslı Çifçibaşi Örmeci
- Bilger Çavuş (ORCID: https://orcid.org/0000-0003-2203-4255)
- Sevim Meşe (ORCID: https://orcid.org/0000-0001-5944-0180)
- Mine Güllüoğlu (ORCID: https://orcid.org/0000-0002-3967-0779)
- Melek Büyük (ORCID: https://orcid.org/0000-0003-3425-2137)
- Mustafa Önel (ORCID: https://orcid.org/0000-0002-3987-6611)
- Elif Eroğlu (ORCID: https://orcid.org/0000-0003-3952-3178)
- Ali Ağaçfidan (ORCID: https://orcid.org/0000-0002-5470-296X)
Institutions
- Istanbul University (TR)
Publication Details
- Journal
- Turkish Journal of Pathology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5146/tjpath.2025.14375
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00