Comparative Analysis Revealed Circulating Methylation of PDGFRB Highly Related with Rheumatoid Arthritis Related Diseases
This study identifies distinct PDGFRB methylation patterns in RA, supporting its potential as a biomarker for diagnosis and differentiation from other rheumatic diseases. The findings open avenues for further exploration of PDGFRB methylation in understanding the epigenetic landscape of autoimmune rheumatic diseases and their potential for clinical applications.
Authors
- Yu Shan (ORCID: https://orcid.org/0000-0003-0979-695X)
- Kai Wei (ORCID: https://orcid.org/0000-0001-7984-1758)
- Yixin Zheng
- Huanru Qu
- Chengzhen Li
- J.-X. Liu (ORCID: https://orcid.org/0000-0003-3248-9325)
- Jianan Zhao (ORCID: https://orcid.org/0000-0002-8439-1082)
- Shicheng Guo (ORCID: https://orcid.org/0000-0002-7047-9972)
- Yi Shen (ORCID: https://orcid.org/0000-0001-5512-4359)
- Chao Liang (ORCID: https://orcid.org/0000-0002-5617-3483)
- Yiming Shi (ORCID: https://orcid.org/0009-0009-9584-0830)
- Cen Chang (ORCID: https://orcid.org/0000-0002-7449-2613)
- Lei Wang (ORCID: https://orcid.org/0000-0003-1802-7466)
- Mi Zhou (ORCID: https://orcid.org/0000-0001-9927-8245)
- Fuyu Zhao
- Mengru Guo (ORCID: https://orcid.org/0000-0002-0896-7182)
- Ping Jiang (ORCID: https://orcid.org/0009-0005-8347-7422)
- Yunshen Li
- Dongyi He (ORCID: https://orcid.org/0009-0009-1963-3805)
Institutions
- Hong Kong Baptist University (HK)
- Southern University of Science and Technology (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine (CN)
Publication Details
- Journal
- Endocrine Metabolic & Immune Disorders - Drug Targets
- Published
- 2025-09-16
- DOI
- https://doi.org/10.2174/0118715303377879250831134649
- Primary Topic
- Eosinophilic Disorders and Syndromes
- Type
- article
- Field-Weighted Citation Impact
- 0.00