Decoding Barberry Root's Therapeutic Network: A Synergistic Solution for IBS-D
SKZ exerts synergistic therapeutic effects on IBS-D by ameliorating inflammation and regulating neurotransmission and intestinal motility, potentially via NF-κB/MAPK, COX- 2/PGE2, cholinergic/5-HT, and calcium/potassium channel pathways, forming a multidimensional network.
Authors
- Xiangwei Wu (ORCID: https://orcid.org/0000-0002-3897-6629)
- Huijiao Jiang
- X L Wang
- Xuan Zhou (ORCID: https://orcid.org/0009-0007-7415-9267)
- Yan Qi
- Xueling Chen
Institutions
- Shihezi University (CN)
- First Affiliated Hospital of Shihezi University Medical College (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-09-15
- DOI
- https://doi.org/10.2174/0113862073421977250903053304
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00