Serum Growth Differentiation Factor 15 Can Be a Novel Biomarker to Predict the Prognosis of Patients With Hepatitis C Virus Cirrhosis After Virus Elimination
Serum GDF15 is a promising prognostic biomarker for post-SVR outcomes in patients with HCV-related cirrhosis. Its ability to predict decompensation and mortality through a validated cutoff supports its use for risk stratification and long-term management in patients with chronic liver disease.
Authors
- Kazuki Maesaka
- Seiichi Mawatari (ORCID: https://orcid.org/0000-0002-3847-1065)
- Takahiro Kodama (ORCID: https://orcid.org/0000-0002-6250-1324)
- Hitoshi Yoshiji (ORCID: https://orcid.org/0000-0002-5243-8544)
- Hisamitsu Miyaaki (ORCID: https://orcid.org/0000-0002-8067-4376)
- Yuta Myojin (ORCID: https://orcid.org/0000-0003-0360-9703)
- Nobuharu Tamaki (ORCID: https://orcid.org/0000-0003-4634-6616)
- Goki Suda (ORCID: https://orcid.org/0000-0003-0098-9106)
- Yoshinobu Saito (ORCID: https://orcid.org/0000-0002-0624-0449)
- Yoshihito Uchida (ORCID: https://orcid.org/0000-0002-6012-0915)
- Yoichi Hiasa (ORCID: https://orcid.org/0000-0003-4117-339X)
- Tetsuo Takehara (ORCID: https://orcid.org/0000-0001-5036-3457)
- Kazuhiro Murai (ORCID: https://orcid.org/0000-0001-8634-2922)
- Daiki Miki (ORCID: https://orcid.org/0000-0002-6505-9826)
- Yuki Tahata (ORCID: https://orcid.org/0000-0002-9116-7054)
- Yuki Makino (ORCID: https://orcid.org/0000-0002-2690-4548)
- Atsunori Tsuchiya (ORCID: https://orcid.org/0000-0002-9279-5917)
- Yōichi Sasaki (ORCID: https://orcid.org/0000-0002-0619-7970)
- Hiroshi Yatsuhashi (ORCID: https://orcid.org/0000-0001-5487-3403)
- Seiya Kato (ORCID: https://orcid.org/0000-0002-8267-2454)
- Kenji Fukumoto
- Hidekatsu Kuroda (ORCID: https://orcid.org/0000-0002-1471-1087)
- Yasuhiro Asahina (ORCID: https://orcid.org/0000-0002-9900-0064)
- Kentaro Matsuura (ORCID: https://orcid.org/0009-0005-0163-3971)
- Taro Takami (ORCID: https://orcid.org/0000-0002-6689-4989)
- Hayato Hikita (ORCID: https://orcid.org/0000-0003-2488-7315)
- Yasunari Nakamoto (ORCID: https://orcid.org/0000-0002-3160-3555)
- Tomohide Tatsumi
- Masaru Enomoto
- Shusuke Kumazaki
- Taro Yamashita (ORCID: https://orcid.org/0000-0002-3383-9131)
- Kumiko Shirai
Institutions
- Kanazawa University (JP)
- Kagoshima University (JP)
- University of Fukui (JP)
- Hiroshima University (JP)
- Osaka Gakuin University (JP)
- University of Nagasaki (JP)
- Yamaguchi University (JP)
- Iwate Medical University (JP)
- Hokkaido University (JP)
- Nagoya City University (JP)
- Kansai Rosai Hospital (JP)
- Nagoya City University Hospital (JP)
- Nagasaki Medical Center (JP)
- Higashihiroshima Medical Center (JP)
- Musashino Red Cross Hospital (JP)
- Ehime University (JP)
- Nagasaki University (JP)
- Osaka Metropolitan University (JP)
- Nara Medical University (JP)
- University of Yamanashi (JP)
- Tokyo Metropolitan University (JP)
- Saitama Medical University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1111/hepr.70041
- Citations
- 3
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 5.00