Clinical profile of COVID-19 among vaccinated and non-vaccinated patients in India

The clinical profile and disease progression among 101 hospitalized COVID-19 patients, comparing 75 vaccinated and 26 non-vaccinated individuals is of interest. Inflammatory marker IL-6 was significantly higher in the non-vaccinated group (P<0.05), while LFT and RFT showed no notable differences. Non-vaccinated patients had lower oxygen saturation at admission and higher ICU admissions and CT scores. Comorbidities like diabetes and hypertension were linked to increased mortality. Thus, vaccinated patients demonstrated better clinical outcomes and fewer complications.