SURGICAL COMPLICATIONS OF CYSTIC FIBROSIS IN PEDIATRIC PRACTICE

Introduction. Cystic fibrosis is one of the world’s most widespread hereditary fatal diseases, which are characteristic of representatives of the white race. Cystic fibrosis is a systemic, genetically determined, autosomal recessive disease characterized by damage to the exocrine glands.The aim is to demonstrate the importance of early diagnosis and treatment of surgical complications of cystic fibrosis in children.Materials and methods. The analysis and generalization of the results of scientific research selected on the basis of an information search in the scientometric databases Scopus, Web of Science, PubMed, MEDLINE, and Google Scholar.The clinical manifestation can vary depending on the exact location of the bezoar and its composition; the diagnosis can be made using CT with contrast enhancement. The formation of fistulas, ulcers, and adhesions are recurrent complications, and severe cases are quite rare.The appearance of a bezoar against the background of cystic fibrosis is primarily associated with insufficiency of the exocrine function of the pancreas, violation of the rheological properties of bile, and violation of the function of the mucous membrane of the gastro-intestinal tract. Patients with cystic fibrosis should not use products that have astringent properties. First of all, such a product is the fruit of a persimmon, which can cause obturation obstruction in the form of a diopsirobezoar even in people without cystic fibrosis.Conclusions. Cystic fibrosis is a multisystem disease that primarily affects the respiratory and digestive systems. However, in pediatric surgical practice, special attention is given to surgical complications. Therefore, when symptoms such as abdominal pain and vomiting occur, prompt evaluation by a pediatric surgeon is essential. In cases where signs of partial intestinal obstruction due to cystic fibrosis are present, initial treatment may consist of conservative therapy, including the use of fibrogastroduodenoscopy. If signs of complete obstructive intestinal obstruction develop, or if conservative methods prove ineffective and the obstruction cannot be resolved endoscopically, surgical intervention remains the only effective treatment.