Combined multiplex polymerase chain reaction-based targeted next−generation sequencing and serum 1, 3-β-D-glucan for differential diagnosis of Pneumocystis pneumonia and Pneumocystis colonization
BALF mp-tNGS and serum BDG serve as valuable adjunct diagnostic tools, providing reliable differentiation between <i>P. jirovecii</i> colonization and active infection.
Authors
- Qizhen Cao (ORCID: https://orcid.org/0000-0002-4601-7989)
- Tao Ren
- Yijun Tang (ORCID: https://orcid.org/0000-0002-8202-7084)
- Xiao Chen (ORCID: https://orcid.org/0000-0002-4224-6450)
- Yunyun Wang (ORCID: https://orcid.org/0000-0002-0102-9898)
- Meifang Wang (ORCID: https://orcid.org/0000-0002-0086-412X)
- Fang Wang (ORCID: https://orcid.org/0000-0002-7032-054X)
- Xiaofeng Wu
- Hansheng Wang (ORCID: https://orcid.org/0000-0003-0342-4178)
- Yi Wu (ORCID: https://orcid.org/0000-0001-9281-7891)
- Yanhui Zhou
Institutions
- Hubei University of Medicine (CN)
- People's Hospital of Shiyan (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-09-18
- DOI
- https://doi.org/10.3389/fcimb.2025.1611391
- Primary Topic
- Pneumocystis jirovecii pneumonia detection and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hubei Province
- Hubei University of Medicine
- Hubei University