Fucosylated N-Glycan Landscape of Triple-Negative Breast Cancer
These findings demonstrate that OAF N-glycans are dynamic, structure-specific markers of TNBC progression and survival, and their early detection and strong prognostic value highlight potential utility in patient stratification and personalized therapy.
Authors
- Laura Spruill (ORCID: https://orcid.org/0000-0003-1895-5203)
- Anand S. Mehta (ORCID: https://orcid.org/0000-0002-9846-9389)
- Graham A. Colditz (ORCID: https://orcid.org/0000-0002-7307-0291)
- Peggi M. Angel (ORCID: https://orcid.org/0000-0002-4436-555X)
- Richard R. Drake (ORCID: https://orcid.org/0000-0002-6285-6440)
- Souvik Seal (ORCID: https://orcid.org/0000-0003-3268-610X)
- Danielle A. Scott (ORCID: https://orcid.org/0000-0003-2461-9812)
- Marvella E. Ford (ORCID: https://orcid.org/0000-0002-7246-9938)
- J. Bruce Dunne (ORCID: https://orcid.org/0009-0005-0258-1368)
Institutions
- Medical University of South Carolina (US)
- Washington University in St. Louis (US)
Publication Details
- Journal
- Molecular Cancer Research
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1158/1541-7786.mcr-25-0483
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of South Carolina
- National Institutes of Health
- Hollings Cancer Center, Medical University of South Carolina
- National Cancer Institute
- National Institute of General Medical Sciences