Sustained Neurotrophic Factor Co-Treatment Enhances Donor and Host Retinal Ganglion Cell Survival in Mice
This study demonstrates that sustained neurotrophic factor delivery can protect vision and improve retinal neuron transplantation outcomes, advancing the treatment of optic neuropathies at both mild and severe stages.
Authors
- Christian Pernstich
- Monichan Phay (ORCID: https://orcid.org/0000-0002-2091-2942)
- John W. Masland
- Jonathan R. Soucy (ORCID: https://orcid.org/0000-0003-1236-1279)
- Petr Baranov (ORCID: https://orcid.org/0000-0002-5526-7058)
- Julia Oswald (ORCID: https://orcid.org/0000-0001-5744-5500)
- Emil Kriukov
Institutions
- Massachusetts Eye and Ear Infirmary (US)
- Harvard University (US)
- Cell Guidance Systems (United Kingdom) (GB)
Publication Details
- Journal
- Translational Vision Science & Technology
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1167/tvst.14.9.27
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00