Elesclomol Diminishes Redox Deficit in Kidney of MBLAC1 Knockout Mice: A Fluorescence Imaging Study
Cryo-imaging analysis revealed lower NADH/FAD redox ratios in MBLAC1 knockout mouse kidneys versus controls. Elesclomol treatment reduced oxidative stress, indicating potential therapeutic applications beyond its established role in cancer treatment.
Authors
- Mehrnoosh Neghabi (ORCID: https://orcid.org/0000-0003-1256-4770)
- Randy Blakely (ORCID: https://orcid.org/0000-0002-2182-6966)
- Anna M. Stauffer
- Mahsa Ranji (ORCID: https://orcid.org/0000-0002-4185-5676)
- Parisa Nategh (ORCID: https://orcid.org/0009-0009-2974-7742)
Publication Details
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1364/cleo_at.2025.jps100_8
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00