Assessment of glycemic control, health-related quality of life, and associated factors in type 2 diabetic patients attending a comprehensive specialized hospital in Northwest Ethiopia

In conclusion, nearly half of the patients were with uncontrolled glycemic level. The majority of participants reported problems in pain/discomfort, usual activities, and anxiety/depression dimensions of HRQoL. Several factors were correlated with both glycemic control and HRQoL. Adherence to antidiabetic medications was positively associated with both glycemic control and HRQoL. In contrast, older age, longer duration of diabetes, presence of comorbidities, diabetic complications, and use of herbal medicine were all negatively associated with both outcomes. On the other hand, adherence to dietary recommendations was positively associated only with glycemic control, while engagement in physical exercise was positively associated only with HRQoL. Moreover, glycemic control was associated with improved HRQoL. The findings underscore the importance of interventions targeting modifiable factors, such as dietary modifications, physical activity, and adherence support, to improve overall glycemic control and HRQoL.