Idiopathic hyperprolactinemia-associated hypogonadism in men presenting with normal testosterone levels

Idiopathic hyperprolactinemia-associated hypogonadism can occasionally present with normal testosterone levels, emphasizing the importance of clinical vigilance beyond standard hormonal assessments. Pituitary height reduction may serve as an important diagnostic marker and indicator of treatment effectiveness. Medical treatment, including bromocriptine or cabergoline, with a possible preference for cabergoline based on clinical considerations, can effectively normalize hormone levels and significantly improve clinical symptoms.

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Publication Details

Journal
PLoS ONE
Published
2025-09-18
DOI
https://doi.org/10.1371/journal.pone.0332871
Primary Topic
Hormonal and reproductive studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Idiopathic hyperprolactinemia-associated hypogonadism in men presenting with normal testosterone levels

Yunbei Xiao, Er Zhou, Xiaozhi Cheng, Qiwen Chen et al.
PLoS ONE
Hormonal and reproductive studies
article

Idiopathic hyperprolactinemia-associated hypogonadism in men presenting with normal testosterone levels

Yunbei Xiao, Er Zhou, Xiaozhi Cheng, Qiwen Chen, Xiao‐Yan Wen, Huiliang Zhou, Yulong Deng
article en

Abstract

Idiopathic hyperprolactinemia-associated hypogonadism can occasionally present with normal testosterone levels, emphasizing the importance of clinical vigilance beyond standard hormonal assessments. Pituitary height reduction may serve as an important diagnostic marker and indicator of treatment effectiveness. Medical treatment, including bromocriptine or cabergoline, with a possible preference for cabergoline based on clinical considerations, can effectively normalize hormone levels and significantly improve clinical symptoms.

PLoS ONEVol. 20(9)
Fujian Medical University (CN), First Affiliated Hospital of Fujian Medical University (CN), Gaozhou People's Hospital (CN)
Openalex Percentile: Top 65%
Hormonal and reproductive studies
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