Inhibition of LncRNA Kcnq1ot1 suppresses hypoxia-induced pyroptosis of H9C2 cells by regulating miR-27b-3p
Collectively, our study demonstrated that inhibition of Kcnq1ot1 protected cardiomyocyte against hypoxia-induced injury possibly via sponging miR-27b-3p, which could be useful as biomarkers and therapeutic targets for HF patients.
Authors
- Yingjie Yang (ORCID: https://orcid.org/0000-0002-3558-9009)
- Jin-Dan Li
- Gary Mo (ORCID: https://orcid.org/0000-0001-7805-5077)
- Yen‐Chuan Ou (ORCID: https://orcid.org/0000-0002-6080-7231)
- Shirong Wang (ORCID: https://orcid.org/0000-0002-1860-2523)
- Limin Liang (ORCID: https://orcid.org/0000-0001-9079-8471)
- Jing Wen (ORCID: https://orcid.org/0000-0002-3227-8539)
Institutions
- Guilin Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1371/journal.pone.0332892
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00