Kidney transplantation and statins effects on dyslipidemia in kidney transplant recipients

In conclusion, KTx was associated with improved HDL levels despite adverse effects on weight and HbA1c levels. The addition of statins to the treatment regimen not only maintained the positive effects of KTx on HDL and TG but also protected against increases in TC and LDL levels. These findings emphasize the potential benefits of KTx on HDL and TG levels in KTRs who received a tacrolimus-based immunosuppression protocol. Statin therapy modulates the LDL and TC increase seen post KTx.

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Publication Details

Journal
Annals of Medicine and Surgery
Published
2025-09-15
DOI
https://doi.org/10.1097/ms9.0000000000003903
Primary Topic
Metabolism and Genetic Disorders
Type
article
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article

Kidney transplantation and statins effects on dyslipidemia in kidney transplant recipients

Abdullah Alghamdi, Tarek Ziad Arabi, Abdulaziz M. Alaklabi, Ziad Arabi et al.
Annals of Medicine and Surgery
Metabolism and Genetic Disorders
article

Kidney transplantation and statins effects on dyslipidemia in kidney transplant recipients

Abdullah Alghamdi, Tarek Ziad Arabi, Abdulaziz M. Alaklabi, Ziad Arabi, Ahmad Alnasrullah, Mohammed Tawhari, Belal Nedal Sabbah, Areez Shafqat, Waleed Fallatah
article en

Abstract

In conclusion, KTx was associated with improved HDL levels despite adverse effects on weight and HbA1c levels. The addition of statins to the treatment regimen not only maintained the positive effects of KTx on HDL and TG but also protected against increases in TC and LDL levels. These findings emphasize the potential benefits of KTx on HDL and TG levels in KTRs who received a tacrolimus-based immunosuppression protocol. Statin therapy modulates the LDL and TC increase seen post KTx.

Annals of Medicine and SurgeryVol. 87(11)
Alfaisal University (SA), King Saud bin Abdulaziz University for Health Sciences (SA), King Abdulaziz Medical City (SA), King Abdullah International Medical Research Center (SA)
Openalex Percentile: Top 72%
Metabolism and Genetic Disorders
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