Pretransplant Immune Checkpoint Inhibitor Treatment for Intermediate-advanced Hepatocellular Carcinoma in Living Donor Liver Transplantation

Selected patients with advanced, initially untransplantable HCC can benefit from a multimodal approach involving LRTs combined with ICIs, enabling successful LT. These findings suggest a potential paradigm shift in the treatment of intermediate-advanced HCC, warranting further investigation in larger cohorts and longer-term studies.

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Publication Details

Journal
Transplantation Direct
Published
2025-09-18
DOI
https://doi.org/10.1097/txd.0000000000001852
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Pretransplant Immune Checkpoint Inhibitor Treatment for Intermediate-advanced Hepatocellular Carcinoma in Living Donor Liver Transplantation

Tse‐Ching Chen, Haowen Shi, Tsung‐Han Wu, Hao‐Chien Hung et al.
Transplantation Direct
Hepatocellular Carcinoma Treatment and Prognosis
article

Pretransplant Immune Checkpoint Inhibitor Treatment for Intermediate-advanced Hepatocellular Carcinoma in Living Donor Liver Transplantation

Tse‐Ching Chen, Haowen Shi, Tsung‐Han Wu, Hao‐Chien Hung, Hong‐Shiue Chou, Jin‐Chiao Lee, Ting-Jung Wu, Chen‐Fang Lee, Yin Lai, Kun‐Ming Chan, Yu-Chao Wang, Wei‐Chen Lee, Chih‐Hsien Cheng
article en

Abstract

Selected patients with advanced, initially untransplantable HCC can benefit from a multimodal approach involving LRTs combined with ICIs, enabling successful LT. These findings suggest a potential paradigm shift in the treatment of intermediate-advanced HCC, warranting further investigation in larger cohorts and longer-term studies.

Transplantation DirectVol. 11(10)
Chang Gung University (TW), Chang Gung Memorial Hospital (TW)
Openalex Percentile: Top 66%
Hepatocellular Carcinoma Treatment and Prognosis
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