Intercenter Variability in the Application of Biopsy-based Transcriptomics in Kidney Transplantation

A moderate discrepancy between histology and MMDx sign-outs was found regardless of the center volume. BBT indications notably varied among centers. Standardized indications should be defined to improve the integration of molecular diagnostics into routine care.

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Publication Details

Journal
Transplantation Direct
Published
2025-09-18
DOI
https://doi.org/10.1097/txd.0000000000001848
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
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article

Intercenter Variability in the Application of Biopsy-based Transcriptomics in Kidney Transplantation

Lucie Capkova, Tomáš Reischig, Luděk Voska, Martina Konkoľová et al.
Transplantation Direct
Renal Transplantation Outcomes and Treatments
article

Intercenter Variability in the Application of Biopsy-based Transcriptomics in Kidney Transplantation

Lucie Capkova, Tomáš Reischig, Luděk Voska, Martina Konkoľová, Zdeněk Lys, Jakub Zieg, Ivana Dedinská, Petra Hruba, Martin Kment, Zuzana Žilinská, Petra Mrázová, Karel Krejčí, Igor Gaľa, Ondřej Viklický, Eva Girmanová, Marek Novotny, M. Kubisova, Vladimír Hanzal
article en

Abstract

A moderate discrepancy between histology and MMDx sign-outs was found regardless of the center volume. BBT indications notably varied among centers. Standardized indications should be defined to improve the integration of molecular diagnostics into routine care.

Transplantation DirectVol. 11(10)
Charles University (CZ), University Hospital Ostrava (CZ), University Hospital Bratislava (SK), University Hospital in Motol (CZ), Pilsen Tools (Czechia) (CZ), University Hospital Olomouc (CZ), Univerzitná Nemocnica Louisa Pasteura (SK), Akadémia Umení v Banskej Bystrici (SK), Institute of Clinical and Experimental Medicine (CZ), University Hospital Hradec Králové (CZ), Slovak Environmental Agency (SK), Martin University Hospital (SK), Comenius University Bratislava (SK)
Openalex Percentile: Top 58%
Renal Transplantation Outcomes and Treatments
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