Testosterone in Duchenne muscular dystrophy: effects on puberty and growth

Measurements of metacarpophalangeal bone length confirms that testosterone therapy enhanced long bone growth in boys with DMD but does not achieve full catch-up growth. Both IM and topical testosterone effectively promote secondary sexual characteristics with no significant side effects.

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Publication Details

Journal
Journal of Pediatric Endocrinology and Metabolism
Published
2025-09-16
DOI
https://doi.org/10.1515/jpem-2025-0329
Primary Topic
Muscle Physiology and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Testosterone in Duchenne muscular dystrophy: effects on puberty and growth

Jennifer Dunne, Iain Horrocks, Sze Choong Wong, Shuko Joseph et al.
Journal of Pediatric Endocrinology and Metabolism
Muscle Physiology and Disorders
article

Testosterone in Duchenne muscular dystrophy: effects on puberty and growth

Jennifer Dunne, Iain Horrocks, Sze Choong Wong, Shuko Joseph, Jane McNeilly, Cara McCauley, Rachel Smillie
article en

Abstract

Measurements of metacarpophalangeal bone length confirms that testosterone therapy enhanced long bone growth in boys with DMD but does not achieve full catch-up growth. Both IM and topical testosterone effectively promote secondary sexual characteristics with no significant side effects.

Journal of Pediatric Endocrinology and MetabolismVol. 38(10)
Royal Hospital for Children (GB), Queen Elizabeth University Hospital (GB), University of Glasgow (GB)
Openalex Percentile: Top 78%
Muscle Physiology and Disorders
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