Efficacy and Safety of Nebulized Midazolam versus Oral Midazolam as Sedative Premedication in Pediatric Surgeries

In pediatric patients undergoing ophthalmic surgeries, nebulized midazolam is as effective as oral midazolam for sedation. The nebulized form is better tolerated and results in significantly improved SpO<sub>2</sub> levels 30 min after administration. These findings indicate that nebulized midazolam is a safe and effective alternative to oral midazolam for sedative premedication in young children.

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Publication Details

Journal
Journal of Current Ophthalmology
Published
2024-10-01
DOI
https://doi.org/10.4103/joco.joco_23_24
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
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article

Efficacy and Safety of Nebulized Midazolam versus Oral Midazolam as Sedative Premedication in Pediatric Surgeries

Saghar Samimi, Alireza Takzare, Parisa Kianpour, Motahhareh Sadeghi et al.
Journal of Current Ophthalmology
Anesthesia and Sedative Agents
article

Efficacy and Safety of Nebulized Midazolam versus Oral Midazolam as Sedative Premedication in Pediatric Surgeries

Saghar Samimi, Alireza Takzare, Parisa Kianpour, Motahhareh Sadeghi, Bita Malekianzadeh, Abbas Ostadalipour, Anahid Maleki, Nima Nazari, Sumaiya Zahra, Armin Sahba
article en

Abstract

In pediatric patients undergoing ophthalmic surgeries, nebulized midazolam is as effective as oral midazolam for sedation. The nebulized form is better tolerated and results in significantly improved SpO<sub>2</sub> levels 30 min after administration. These findings indicate that nebulized midazolam is a safe and effective alternative to oral midazolam for sedative premedication in young children.

Journal of Current OphthalmologyVol. 36(4)
Farabi Hospital (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 52%
Anesthesia and Sedative Agents
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