Exploring the top 30 drugs associated with drug-induced thrombotic microangiopathy based on the FDA adverse event reporting system
Our comprehensive analysis of drug rankings and signal strengths associated with TMA in FAERS underscores the critical role of pharmacovigilance in identifying and understanding drug-induced TMA. These findings necessitate further research to validate the observed associations and to develop effective risk management strategies, ultimately improving patient outcomes. This study provides valuable evidence to support the accurate clinical identification of drug-related TMA.
Authors
- Yi Yin
- Yuqi Fan (ORCID: https://orcid.org/0000-0002-0084-2895)
- Fanmin Meng (ORCID: https://orcid.org/0009-0002-4399-6816)
Institutions
- Shandong Provincial Hospital (CN)
- Central Hospital of Zibo (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-18
- DOI
- https://doi.org/10.3389/fphar.2025.1658963
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00