Disentangling the contributions of cerebrovascular-related white matter integrity markers to cognitive aging
This study identified both cross-sectional and longitudinal associations between five markers of white matter integrity and cognitive performance and decline. Using BMA-a method designed to disentangle the specific contribution of each marker while accounting for multicollinearity-we found that, among the five markers, FW and WMH emerged as the most probable candidates to explain the course of cognitive decline in EM and EF.
Authors
- David K. Johnson (ORCID: https://orcid.org/0000-0003-3670-8054)
- Pauline Maillard (ORCID: https://orcid.org/0000-0003-3516-6345)
- Charles DeCarli (ORCID: https://orcid.org/0000-0003-1914-2693)
- Elmira Agah (ORCID: https://orcid.org/0000-0001-8541-8075)
- Sarah Tomaszewski Farias (ORCID: https://orcid.org/0009-0009-8969-3387)
Institutions
- Center for Neurosciences (US)
- University of California, Davis (US)
Publication Details
- Journal
- Cerebral Circulation - Cognition and Behavior
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.cccb.2025.100395
- Citations
- 1
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.36