Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment—secondary outcomes from the SYNERGIC trial
Aerobic-resistance exercise combined with sequential computerised cognitive training improved gait performance at 6 months and decreased the risk of falls and injuries at 12 months in older adults with MCI. The addition of vitamin D did not produce benefits.
Authors
- Mark Speechley (ORCID: https://orcid.org/0000-0002-7563-8709)
- Frederico Pieruccini‐Faria (ORCID: https://orcid.org/0000-0002-7659-4285)
- Louis Bherer (ORCID: https://orcid.org/0000-0003-2258-8194)
- Maxime Lussier (ORCID: https://orcid.org/0000-0003-2753-1189)
- Laura Elizabeth Middleton (ORCID: https://orcid.org/0000-0001-8624-3123)
- Quincy J. Almeida (ORCID: https://orcid.org/0000-0002-0806-4397)
- Richard Camicioli (ORCID: https://orcid.org/0000-0003-2977-8660)
- Manuel Montero‐Odasso (ORCID: https://orcid.org/0000-0002-5796-2361)
- Nicolas Berryman (ORCID: https://orcid.org/0000-0002-4868-7986)
- Guangyong Zou (ORCID: https://orcid.org/0000-0001-5773-4185)
- Nick W. Bray (ORCID: https://orcid.org/0000-0001-5831-7842)
- Karen Li (ORCID: https://orcid.org/0000-0002-0261-743X)
- Surim Son
- Teresa Y L Liu-Ambrose (ORCID: https://orcid.org/0000-0002-8297-5308)
- Amer M. Burhan (ORCID: https://orcid.org/0000-0002-9888-008X)
- J. Kevin Shoemaker (ORCID: https://orcid.org/0000-0002-6794-5979)
- Sarah Fraser (ORCID: https://orcid.org/0000-0003-4291-6298)
Institutions
- Western University (CA)
- Memorial University of Newfoundland (CA)
- Vancouver Coastal Health (CA)
- University of British Columbia (CA)
- University of Waterloo (CA)
- University of Ottawa (CA)
- Université du Québec à Montréal (CA)
- University of Toronto (CA)
- Montreal Heart Institute (CA)
- Ontario Shores Centre for Mental Health Sciences (CA)
- Institut National de Santé Publique du Québec (CA)
- Parkwood Institute (CA)
- Institut Universitaire de Gériatrie de Montréal (CA)
- Women and Children’s Health Research Institute (CA)
- Institut universitaire de cardiologie et de pneumologie de Québec (CA)
- Research Institute for Aging (CA)
- Mayo Clinic in Florida (US)
- Vancouver Coastal Health Research Institute (CA)
- Montreal Clinical Research Institute (CA)
- Concordia University (CA)
- Université de Montréal (CA)
Publication Details
- Journal
- Age and Ageing
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1093/ageing/afaf242
- Citations
- 4
- Primary Topic
- Balance, Gait, and Falls Prevention
- Type
- article
- Field-Weighted Citation Impact
- 19.04