Guiding Antiviral Cell Therapy Approaches with an Online Resource of Clinically Scored Epitopes, T-Cell Receptors, and B-Cell Receptors
Redirecting T-cell specificity by genetic engineering using clinically protective TCR or CAR sequences will not only bring significant progress to the field of adoptive T-cell therapies but also lay the groundwork for broader applications such as off-the-shelf approaches.
Authors
- Elvira D’Ippolito (ORCID: https://orcid.org/0000-0003-0113-6797)
- Florian Kohlmayer (ORCID: https://orcid.org/0000-0002-5384-0076)
- Michael Decker (ORCID: https://orcid.org/0000-0002-6773-6245)
- Tobias F. Feuchtinger (ORCID: https://orcid.org/0000-0002-8517-9681)
- Josef Mautner (ORCID: https://orcid.org/0000-0002-8680-1065)
- Uta Behrends (ORCID: https://orcid.org/0000-0002-8693-4386)
- Britta Eiz‐Vesper (ORCID: https://orcid.org/0000-0001-8378-3298)
- Christoph Kreer (ORCID: https://orcid.org/0000-0002-9140-9850)
- Andreas Moosmann (ORCID: https://orcid.org/0000-0001-8044-5146)
- Britta Maecker‐Kolhoff (ORCID: https://orcid.org/0000-0001-8164-514X)
- Dirk Hans Busch (ORCID: https://orcid.org/0000-0001-8713-093X)
- Semjon Manuel Willier (ORCID: https://orcid.org/0000-0001-9472-2191)
- Florian Klein (ORCID: https://orcid.org/0000-0003-1376-1792)
- A Menzel
- Theresa Kaeuferle (ORCID: https://orcid.org/0009-0005-2122-7794)
- Mira Reger (ORCID: https://orcid.org/0009-0008-2941-9231)
- Lilli Gutjahr
Institutions
- University of Cologne (DE)
- University Medical Center Freiburg (DE)
- Helmholtz Zentrum München (DE)
- LMU Klinikum (DE)
- Medizinische Hochschule Hannover (DE)
- German Center for Infection Research (DE)
- Helmholtz-Institute Ulm (DE)
- Institute of Medical Microbiology and Hygiene (DE)
- University Hospital Cologne (DE)
- Technical University of Munich (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Transfusion Medicine and Hemotherapy
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1159/000548312
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00