Maternal Immunoglobulin Treatment of Gestational Alloimmune Liver Disease to Prevent Neonatal Liver Failure: A Single Center Case Series

This case series indicates that weekly antenatal IVIG treatment is highly efficient to prevent GALD-associated neonatal liver failure. In contrast to other cases series, there were no major maternal side effects. An introduced novel laboratory scoring system to decide on early postnatal intervention requires validation in a larger number of neonates.

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Publication Details

Journal
Transfusion Medicine and Hemotherapy
Published
2025-09-18
DOI
https://doi.org/10.1159/000548476
Citations
1
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
1.82
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article

Maternal Immunoglobulin Treatment of Gestational Alloimmune Liver Disease to Prevent Neonatal Liver Failure: A Single Center Case Series

Beate Mayer, Christof Dame, Caroline Gabrysch, Christoph Bührer et al.
1 citations
Transfusion Medicine and Hemotherapy
Diabetes and associated disorders
1.82
article

Maternal Immunoglobulin Treatment of Gestational Alloimmune Liver Disease to Prevent Neonatal Liver Failure: A Single Center Case Series

Beate Mayer, Christof Dame, Caroline Gabrysch, Christoph Bührer, Iris Dressler‐Steinbach, Stefan Verlohren
article en
1 citations

Abstract

This case series indicates that weekly antenatal IVIG treatment is highly efficient to prevent GALD-associated neonatal liver failure. In contrast to other cases series, there were no major maternal side effects. An introduced novel laboratory scoring system to decide on early postnatal intervention requires validation in a larger number of neonates.

Transfusion Medicine and HemotherapyVol. 52(6)
Humboldt-Universität zu Berlin (DE), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 12%
Diabetes and associated disorders
1.82
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Maternal Immunoglobulin Treatment of Gestational Alloimmune Liver Disease to Prevent Neonatal Liver Failure: A Single Center Case Series — Beate Mayer, Christof Dame, et al. · Transfusion Medicine and Hemotherapy (2025) | TGRS Research Map | TGRS