Cardiometabolic outcomes in girls with premature adrenarche: a longitudinal analysis of typical vs. exaggerated presentations
Elevated mid-childhood DHEAS does not independently predict worsened metabolic outcomes by puberty. Baseline adiposity, not androgen level, is the principal determinant of insulin resistance and cardiometabolic risk in PA. Lifestyle interventions targeting weight management are crucial in mitigating future risk.
Authors
- Şükrü Hatun (ORCID: https://orcid.org/0000-0003-1633-9570)
- Gülcan Seymen Karabulut (ORCID: https://orcid.org/0000-0003-0614-4083)
- M Imal
Institutions
- Kocaeli Üniversitesi (TR)
Publication Details
- Journal
- Journal of Pediatric Endocrinology and Metabolism
- Published
- 2025-09-15
- DOI
- https://doi.org/10.1515/jpem-2025-0232
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00