Analysis of 24-Hour Blood Pressure Profile and Antihypertensive Therapy in Male Heart Transplant Patients

<b>Background</b>: Although there has been an improvement in the survival rates of patients following heart transplantation, many complications, such as hypertension, continue to develop. The aim of the study was to assess the 24-hour blood pressure profile and hypertension treatment among patients after heart transplantation and comparison to the control group. <b>Methods</b>: A retrospective data analysis included 26 male patients post-heart transplantation and 39 male patients in the control group. During a routine visit, the following data were collected: 24-hour blood pressure monitoring, laboratory tests, and medical history. <b>Results</b>: Hypertension was diagnosed in 76.9% of heart transplant recipients (HTXr) and in 56.4% of the control group (Cx). During the night-time rest period, diastolic blood pressure values ≥ 70 mmHg were observed in 76.9% of HTXr (vs. 33.33% Cx, <i>p</i> = 0.001). The average daytime systolic/diastolic blood pressure did not differ significantly between the groups. It was also observed that the groups differed in circadian blood pressure (Chi<sup>2</sup>ML = 15.87, <i>p</i> < 0.001), as there were significantly more reverse dippers in HTXr than in the control group (30.8% (8) vs. 10.3% (4)). The same proportions were also noted in HTXr and the control group in terms of isolated nocturnal hypertension. <b>Conclusions</b>: Heart transplant recipients require a tailored approach to hypertension management, including a variety of medications and appropriate chronotherapy.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2025-09-18
DOI
https://doi.org/10.3390/jcm14186590
Primary Topic
Transplantation: Methods and Outcomes
Type
article
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article

Analysis of 24-Hour Blood Pressure Profile and Antihypertensive Therapy in Male Heart Transplant Patients

Wioletta Jastrzębska, Alicja Radtke-Łysek, Michał Bohdan, Anna Frankiewicz et al.
Journal of Clinical Medicine
Transplantation: Methods and Outcomes
article

Analysis of 24-Hour Blood Pressure Profile and Antihypertensive Therapy in Male Heart Transplant Patients

Wioletta Jastrzębska, Alicja Radtke-Łysek, Michał Bohdan, Anna Frankiewicz, Wojciech Sobiczewski, Marcin Gruchała
article en

Abstract

<b>Background</b>: Although there has been an improvement in the survival rates of patients following heart transplantation, many complications, such as hypertension, continue to develop. The aim of the study was to assess the 24-hour blood pressure profile and hypertension treatment among patients after heart transplantation and comparison to the control group. <b>Methods</b>: A retrospective data analysis included 26 male patients post-heart transplantation and 39 male patients in the control group. During a routine visit, the following data were collected: 24-hour blood pressure monitoring, laboratory tests, and medical history. <b>Results</b>: Hypertension was diagnosed in 76.9% of heart transplant recipients (HTXr) and in 56.4% of the control group (Cx). During the night-time rest period, diastolic blood pressure values ≥ 70 mmHg were observed in 76.9% of HTXr (vs. 33.33% Cx, <i>p</i> = 0.001). The average daytime systolic/diastolic blood pressure did not differ significantly between the groups. It was also observed that the groups differed in circadian blood pressure (Chi<sup>2</sup>ML = 15.87, <i>p</i> < 0.001), as there were significantly more reverse dippers in HTXr than in the control group (30.8% (8) vs. 10.3% (4)). The same proportions were also noted in HTXr and the control group in terms of isolated nocturnal hypertension. <b>Conclusions</b>: Heart transplant recipients require a tailored approach to hypertension management, including a variety of medications and appropriate chronotherapy.

Journal of Clinical MedicineVol. 14(18)
Gdańsk Medical University (PL)
Openalex Percentile: Top 59%
Transplantation: Methods and Outcomes
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Analysis of 24-Hour Blood Pressure Profile and Antihypertensive Therapy in Male Heart Transplant Patients — Wioletta Jastrzębska, Alicja Radtke-Łysek, et al. · Journal of Clinical Medicine (2025) | TGRS Research Map | TGRS