Epilepsy surgery for seizure control in individuals with Dravet syndrome: is it a safe and practical option?

In general, people with Dravet syndrome are rarely favorable candidates for epilepsy surgery, yet surgery is not necessarily contraindicated. Meaningful seizure reduction can be achieved in highly selected cases with perhaps the most benefit arising from neuromodulation procedures such as vagus nerve stimulation. It remains uncertain whether seizure reduction following surgery contributes to any non-seizure benefits.

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Publication Details

Journal
Expert Review of Neurotherapeutics
Published
2025-09-18
DOI
https://doi.org/10.1080/14737175.2025.2562118
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Epilepsy surgery for seizure control in individuals with Dravet syndrome: is it a safe and practical option?

Michael Scott Perry, Elaine C. Wirrell, Keith Starnes
Expert Review of Neurotherapeutics
Epilepsy research and treatment
article

Epilepsy surgery for seizure control in individuals with Dravet syndrome: is it a safe and practical option?

Michael Scott Perry, Elaine C. Wirrell, Keith Starnes
article en

Abstract

In general, people with Dravet syndrome are rarely favorable candidates for epilepsy surgery, yet surgery is not necessarily contraindicated. Meaningful seizure reduction can be achieved in highly selected cases with perhaps the most benefit arising from neuromodulation procedures such as vagus nerve stimulation. It remains uncertain whether seizure reduction following surgery contributes to any non-seizure benefits.

Expert Review of NeurotherapeuticsVol. 25(11)
Mayo Clinic (US), WinnMed (US), Cook Children's Medical Center (US)
Openalex Percentile: Top 70%
Epilepsy research and treatment
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