Metformin and the Development of Age-Related Macular Degeneration
This study suggests that, overall, metformin is not associated with significant development or progression of AMD. Further studies and prospective analyses are necessary to evaluate whether dosage and longevity of metformin use are associated with AMD development or progression.
Authors
- Darren A Jindal
- Jonathan Markle (ORCID: https://orcid.org/0000-0002-0543-9229)
- Aleksandra Rachitskaya (ORCID: https://orcid.org/0000-0001-5545-9474)
- David C. Kaelber (ORCID: https://orcid.org/0000-0001-7855-9515)
- Jacqueline K. Shaia (ORCID: https://orcid.org/0000-0001-7873-669X)
- Katherine E. Talcott (ORCID: https://orcid.org/0000-0003-0458-4181)
- Jovana Hanna (ORCID: https://orcid.org/0000-0002-4543-6081)
- Rishi P. Singh
Institutions
- MetroHealth (US)
- Cleveland Clinic (US)
- Wright State University (US)
- Cleveland Clinic Florida (US)
- University School (US)
- Cleveland Eye Clinic (US)
- Case Western Reserve University (US)
- Northeast Ohio Medical University (US)
Publication Details
- Journal
- JAMA Ophthalmology
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1001/jamaophthalmol.2025.3070
- Citations
- 3
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.12