Imaging Differentiation of Supratentorial Ependymoma and High-Grade Glioma in Children Using VASARI Features
Although sEPN and sHGG share overlapping imaging characteristics, a combination of 16 routine MRI features can fully differentiate them. Smaller subsets of 2 features (calcifications with definition of nonenhancing margins or the definitions of both enhancing and nonenhancing margins) also provide high diagnostic accuracy. These feature combinations improve differentiation and may support more informed treatment decisions, potentially leading to better patient outcomes.
Authors
- Arastoo Vossough (ORCID: https://orcid.org/0000-0003-1346-427X)
- Luis Octavio Tierradentro‐García (ORCID: https://orcid.org/0000-0003-1164-4656)
- Angela N. Viaene (ORCID: https://orcid.org/0000-0001-6430-8360)
- Fabrício Guimarães Gonçalves (ORCID: https://orcid.org/0000-0002-8889-9879)
- Carmen Cerron-Vela (ORCID: https://orcid.org/0000-0002-7881-6021)
- Aashim Bhatia (ORCID: https://orcid.org/0000-0002-3702-9304)
Institutions
- Children's Hospital of Philadelphia (US)
- Children's of Alabama (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-09-16
- DOI
- https://doi.org/10.3174/ajnr.a9001
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00