Mass Spectrometric Measurements of 11‐Deoxycortisol, Androstenedione and Dehydroepiandrosterone Are Superior to Cortisol to Assess Selectivity of Non‐Stimulated Adrenal Vein Sampling
11-Deoxycortisol, androstenedione and dehydroepiandrosterone are more suitable biomarkers than cortisol to assess AVS selectivity and allow rescue of many procedures otherwise deemed unsuccessful. Measurements of cortisol to assess AVS selectivity are best replaced by mass spectrometric measurements of other steroids.
Authors
- Christina Pamporaki (ORCID: https://orcid.org/0000-0003-0772-1604)
- Hanna Remde (ORCID: https://orcid.org/0000-0002-3499-5910)
- Jacques W.M. Lenders (ORCID: https://orcid.org/0000-0002-7658-4466)
- Felix Beuschlein (ORCID: https://orcid.org/0000-0001-7826-3984)
- Martín Reincke (ORCID: https://orcid.org/0000-0002-9817-9875)
- Manuel Schulze (ORCID: https://orcid.org/0009-0008-5819-0835)
- Sybille Fuld (ORCID: https://orcid.org/0009-0000-8560-9920)
- Mirko Peitzsch (ORCID: https://orcid.org/0000-0002-2472-675X)
- Carmina Teresa Fuß (ORCID: https://orcid.org/0000-0002-1466-5287)
- Graeme Eisenhofer (ORCID: https://orcid.org/0000-0002-8601-9903)
- Lydia Kürzinger
- Jun Yang (ORCID: https://orcid.org/0000-0003-4620-4976)
- Georgiana Constantinescu (ORCID: https://orcid.org/0000-0002-7304-2557)
- Sradha S. Kotwal (ORCID: https://orcid.org/0000-0002-3294-4087)
- Francesco Alessi
Institutions
- Radboud University Nijmegen (NL)
- University of Würzburg (DE)
- Hudson Institute of Medical Research (AU)
- Radboud University Medical Center (NL)
- University Hospital of Zurich (CH)
- The George Institute for Global Health (AU)
- Universitätsklinikum Würzburg (DE)
- University Hospital Carl Gustav Carus (DE)
- Technische Universität Dresden (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Clinical Endocrinology
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1111/cen.70037
- Citations
- 1
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Deutsche Forschungsgemeinschaft
- Universität Zürich