A miRNA signature linked to high lipoprotein (a) and coronary calcification in familial hypercholesterolaemia
Our results identify a miRNA signature that regulates atherosclerotic processes associated with high Lp(a) levels and CAC in asymptomatic FH patients. These findings offer new insights into the underlying mechanisms and highlight potential therapeutic targets.
Authors
- Marta Mauri (ORCID: https://orcid.org/0000-0002-2042-5829)
- Lina Badimón (ORCID: https://orcid.org/0000-0002-9162-2459)
- Juan Francisco Sánchez Muñoz-Torrero (ORCID: https://orcid.org/0000-0003-0055-8875)
- Teresa Padró (ORCID: https://orcid.org/0000-0003-1921-954X)
- Rafael Escate (ORCID: https://orcid.org/0000-0002-8448-7244)
- Pedro Mata
Institutions
- Universitat de Vic - Universitat Central de Catalunya (ES)
- Instituto de Salud Carlos III (ES)
- Hospital de Sant Pau (ES)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Hospital Terrassa (ES)
- Hospital San Pedro de Alcántara (ES)
- Centro de Investigación Biomédica en Red de Cáncer (ES)
Publication Details
- Journal
- Computational and Structural Biotechnology Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.csbj.2025.09.026
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00