Photoinduced iron-catalyzed C(sp<sup>3</sup>)–H alkylation of simple hydrocarbons with Morita–Baylis–Hillman acetates
Direct C(sp<sup>3</sup>)-H bond functionalization of aliphatic hydrocarbons represents an ideal strategy for accessing high-value-added chemicals, yet it remains a daunting task. Herein, we report a photoinduced iron-catalyzed system for the direct C(sp<sup>3</sup>)-H bond alkylation of simple alkanes with Morita-Baylis-Hillman acetates <i>via</i> a ligand-to-metal charge transfer process. This protocol operates under redox-neutral conditions, demonstrates broad functional group tolerance and delivers good to excellent yields.
Authors
- Yuhan Yang (ORCID: https://orcid.org/0000-0002-9004-8192)
- Mingsong Shi (ORCID: https://orcid.org/0000-0002-8979-5844)
- Yan Zhou (ORCID: https://orcid.org/0000-0002-7290-1401)
- Lin‐Hai Jing (ORCID: https://orcid.org/0000-0001-6424-4491)
- Qiang Xiao (ORCID: https://orcid.org/0000-0003-2976-5042)
- Dan Yang (ORCID: https://orcid.org/0000-0001-9984-7225)
Institutions
- University of Electronic Science and Technology of China (CN)
- China West Normal University (CN)
- Mianyang Central Hospital (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc04093k
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00