Spherical nanoflower-shaped Co-2MI with laccase-like activity for colorimetric detection of salbutamol
A Co MOF (Co-2MI) nanozyme with uniform spherical nanoflower morphology was constructed with efficient laccase-like activity. Co-2MI displayed lower <i>K</i> <sub>m</sub> and higher <i>V</i> <sub>max</sub> than natural Laccase, indicating stronger substrate affinity and superior catalytic efficiency. Mechanistic investigations confirmed an ˙O<sub>2</sub> <sup>-</sup>-mediated oxidation pathway. Based on its laccase-like activity, we established a novel colorimetric method for Salbutamol detection, obtaining a linear range of 1-60 μg mL<sup>-1</sup> and a low detection limit of 0.91 μg mL<sup>-1</sup>. Finally, the Co-2MI nanozyme was successfully applied to the colorimetric detection of Salbutamol in real samples.
Authors
- Lili Xu (ORCID: https://orcid.org/0000-0001-6899-971X)
- Jianli Nan
- Shaojun Dong (ORCID: https://orcid.org/0000-0002-0263-6577)
- Youxing Fang (ORCID: https://orcid.org/0000-0003-0888-1730)
- Songxue Han (ORCID: https://orcid.org/0009-0005-1439-3356)
Institutions
- University of Science and Technology of China (CN)
- Sun Yat-sen University (CN)
- Jilin University (CN)
- Chinese Academy of Sciences (CN)
- Changchun Institute of Applied Chemistry (CN)
Publication Details
- Journal
- RSC Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ra05134g
- Citations
- 1
- Primary Topic
- Advanced Nanomaterials in Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.52
Funders
- National Natural Science Foundation of China
- People's Government of Jilin Province