Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays

Four NfL assays demonstrated similar analytic performance. Alongside performance, other factors such as costs, accessibility, usability, footprint, and intended use, should be considered.

Authors

Institutions

Publication Details

Journal
Clinical Chemistry and Laboratory Medicine (CCLM)
Published
2025-09-08
DOI
https://doi.org/10.1515/cclm-2025-0610
Citations
2
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
2.78
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article

Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays

Emeline Daniel, Danielle Graham, Michael Benatar, Kyle Ferber et al.
2 citations
Clinical Chemistry and Laboratory Medicine (CCLM)
Amyotrophic Lateral Sclerosis Research
2.78
article

Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays

Emeline Daniel, Danielle Graham, Michael Benatar, Kyle Ferber, Erin G. Rosenbaugh, Laura L. Mitic, Rebecca Harrison, Udit Sheth, Amanda Bevis, Tania F. Gendron, Nicole L. Bjorklund, Yongge Liu, Henrik Zetterberg, Glenn A. Harris, Olga I. Kahn, Rohini Khillan
article en
2 citations

Abstract

Four NfL assays demonstrated similar analytic performance. Alongside performance, other factors such as costs, accessibility, usability, footprint, and intended use, should be considered.

Clinical Chemistry and Laboratory Medicine (CCLM)Vol. 64(2)
Biogen (United States) (US), University of Miami (US), Foundation for the National Institutes of Health (US), Sahlgrenska University Hospital (SE), Jacksonville College (US), Bluefield College (US), Rainwater Charitable Foundation (US), Institute for Neurodegenerative Disorders (US), UK Dementia Research Institute (GB), Association for Frontotemporal Degeneration (US), Otsuka Pharmaceutical (Spain) (ES), Mayo Clinic in Florida (US), Alector (United States) (US), University College London (GB), GW Pharmaceuticals (United Kingdom) (GB), University of Gothenburg (SE)
Openalex Percentile: Top 9%
Amyotrophic Lateral Sclerosis Research
2.78
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Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays — Emeline Daniel, Danielle Graham, et al. · Clinical Chemistry and Laboratory Medicine (CCLM) (2025) | TGRS Research Map | TGRS