Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays
Four NfL assays demonstrated similar analytic performance. Alongside performance, other factors such as costs, accessibility, usability, footprint, and intended use, should be considered.
Authors
- Emeline Daniel
- Danielle Graham (ORCID: https://orcid.org/0000-0003-2922-6268)
- Michael Benatar (ORCID: https://orcid.org/0000-0003-4241-5135)
- Kyle Ferber (ORCID: https://orcid.org/0000-0002-4730-6993)
- Erin G. Rosenbaugh (ORCID: https://orcid.org/0000-0002-3909-9760)
- Laura L. Mitic (ORCID: https://orcid.org/0000-0002-0183-4272)
- Rebecca Harrison
- Udit Sheth (ORCID: https://orcid.org/0000-0003-4360-7892)
- Amanda Bevis
- Tania F. Gendron (ORCID: https://orcid.org/0000-0002-7335-2627)
- Nicole L. Bjorklund (ORCID: https://orcid.org/0000-0002-8296-7623)
- Yongge Liu (ORCID: https://orcid.org/0009-0002-6639-9432)
- Henrik Zetterberg (ORCID: https://orcid.org/0000-0002-4671-6763)
- Glenn A. Harris
- Olga I. Kahn
- Rohini Khillan
Institutions
- Biogen (United States) (US)
- University of Miami (US)
- Foundation for the National Institutes of Health (US)
- Sahlgrenska University Hospital (SE)
- Jacksonville College (US)
- Bluefield College (US)
- Rainwater Charitable Foundation (US)
- Institute for Neurodegenerative Disorders (US)
- UK Dementia Research Institute (GB)
- Association for Frontotemporal Degeneration (US)
- Otsuka Pharmaceutical (Spain) (ES)
- Mayo Clinic in Florida (US)
- Alector (United States) (US)
- University College London (GB)
- GW Pharmaceuticals (United Kingdom) (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-09-08
- DOI
- https://doi.org/10.1515/cclm-2025-0610
- Citations
- 2
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 2.78