Performance evaluation of quantitative hemoglobin A <sub>2</sub> and fetal hemoglobin testing using commercially lyophilized vs. in-house whole blood controls in Chinese clinical laboratories: a 12-year analysis of National External Quality Assessmen
In-house controls demonstrate homogeneity, stability and intrinsic commutability, and have an expanded concentration range, can serve as a reliable alternative to commercial controls for EQA. High-precision techniques such as CE should be favoured. Furthermore, the development of reference methods and commutable reference materials is essential for standardization.
Authors
- Chenbin Li (ORCID: https://orcid.org/0000-0003-2434-7140)
- Gaofeng Hu
- Juan Tang (ORCID: https://orcid.org/0000-0002-7742-7948)
- Yu-Kun Han
- Jie Ma (ORCID: https://orcid.org/0000-0002-7419-136X)
- Yating Ma (ORCID: https://orcid.org/0000-0003-1261-4475)
- Zhongli Du
- Chengshan Xu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
- National Center for Clinical Laboratories (CN)
- Riverside Hospital of Guangxi Zhuang Autonomous Region (CN)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-09-08
- DOI
- https://doi.org/10.1515/cclm-2025-0683
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00