Hypokalaemia Induced by Renal Tubular Acidosis in a Patient with Sjogren’s Syndrome: A Case Report

In this case study, a 38-year woman was diagnosed with distal renal tubular acidosis (RTA) secondary to Sjogren's Syndrome (SS) after presenting with recurrent episodes of sudden-onset quadriparesis, hypokalaemia (serum potassium: 1.07 mmol/L), and metabolic acidosis (HCO 3 : 15.9 mmol/L).Positive anti-SSA/Ro antibodies (55.96U/mL), an elevated erythrocyte sedimentation rate (ESR: 65 mm/1 st hour), and autoimmune serology results confirmed the diagnosis even in the absence of characteristic sicca symptoms.Distal RTA, a recognised SS complication, was confirmed by the patient's alkaline urine (pH 7.0) and high spot urine potassium-to-creatinine ratio (43 mEq/g).Potassium supplements, sodium bicarbonate for acidosis, and immunosuppression with steroids, hydroxychloroquine, and azathioprine were all part of the treatment.In addition to highlighting the significance of autoimmune examination in patients with unexplained hypokalaemia and RTA, this case also shows the diagnostic difficulties of SS in the absence of classic glandular signs.To avoid complications and improve the outcomes, it is essential to identify and treat SS-related renal and electrolyte abnormalities as soon as possible.