Transurethral Resection of Prostate in Benign Prostatic Obstruction associated with Overactive Bladder: Outcome and Prognostic factors

Background: Enlargement of the prostate and other lower urinary tract symptoms are typical in older men with benign prostatic hyperplasia (BPH). Most treatments for LUTS/BPH have traditionally focused on relieving obstruction since bladder outlet obstruction (BOO) has long been thought to play a significant role in the process by which BPH generates LUTS. Aim and objectives: To evaluate the outcome of TURP in patients presented with benign prostatic obstruction (BPO) and overactive bladder (OAB), and to assess the predictive factors for improvement in OAB (storage symptoms). Patients and methods: This interventional, prospective, purposive, study was conducted on 50 adult male patients during the period from June 2022 to July 2024 at the Urology Department, Sayed Galal and Al-Hussien University Hospitals; Cairo; Egypt. The research ethics committee of our institution approved the study protocol and all participants signed an informed consent before inclusion. Results: There were notable improvements in the overall voiding function as measured by Qmax, PVR, and the International Prostate Symptom Score (IPSS). Similarly, there were notable improvements in storage symptoms as measured by OABSS, QOLS, and urodynamic findings. Conclusion: TURP is considered a reliable treatment option for patients with BPO and OAB with a significant improvement of their overactive bladder symptom score (OABSS) and quality of life score, also duration of symptoms is considered the only predictive factor for improvement of symptoms after TURP.