Analysis of current status and influencing factors on quality of life in patients with spinal metastases

Objective To explore the status quo and influencing factors of quality of life in patients with spinal metastases. Methods From January 2024 to November 2024, 143 patients with spinal metastasis in Chongqing cancer hospital were selected by the convenience sampling method. The tools used were Europe Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Bone Metastases22(EORTC QLQ-BM22), Hospital Anxiety and Depression Scale(HADS), Brief Fatigue Inventory(BFI-C)and Barthel index. Results Patients scored (46. 70±8. 93) points in Preoperative quality of life evaluated by EORTC QLQ-BM22. There were statistically significant differences in the total score of quality of life among patients with different sleep and self-care abilities and different degrees of anxiety, depression, and fatigue(P＜0. 05). The EORTC QLQ-BM22 scores of patients with spinal metastases were positively correlated with anxiety, depression, and fatigue, with correlation coefficients of 0. 448, 0. 309, and 0. 450, respectively, and the differences were statistically significant(P＜0. 05). Multiple linear regression analysis showed that sleep, anxiety, and fatigue are independent influencing factors on patients 'quality of life, jointly explained 44. 5% variation in quality of life. Conclusion The quality of life of patients with spinal metastases is not optimistic. While focusing on the improvement of physical function symptoms, attention should be paid to the screening and intervention of psychological disorders. Medical staff can incorporate quality of life into routine assessment and prognosis assessment of patients with bone metastases, which is conducive to the formulation of individualized treatment plans. (目的 探讨恶性肿瘤伴脊柱转移患者生存质量的现状及影响因素。方法 选取2024年1月—12月于重庆某三级甲等肿瘤专科医院住院治疗的143例脊柱转移瘤患者, 采用骨转移瘤患者生存质量调查问卷(EORTC QLQ-BM22)、医院焦虑抑郁量表(HADS)、简明疲乏量表(BFI-C)、Barthel指数(BI)对其进行调查。结果 脊柱转移瘤患者生存质量得分(46. 70±8. 93)分。不同睡眠、自理能力的患者生存质量总分比较, 差异有统计学意义(P＜0. 05)。不同程度焦虑、抑郁、疲乏的脊柱转移瘤患者生存质量得分比较差异有统计学意义(P＜0. 05), 脊柱转移瘤患者生存质量得分与焦虑(r=0. 448)、抑郁(r=0. 309)、疲乏呈正相关(r=0. 450), 差异有统计学意义(P＜0. 05), 多元线性回归分析显示: 睡眠、焦虑、疲乏为患者生存质量的独立影响因素, 可解释44. 5%的变异量。结论 脊柱转移瘤患者的生存质量不容乐观, 在关注躯体功能症状改善的同时, 应重视心理障碍的筛查与干预。医护人员可将生存质量纳入骨转移患者的常规评估及预后评估, 有利于制定个性化的支持性治疗。)