Mouse model validity for studying the impact of tobacco smoke on the human gut microbiota assessed via <i>in silico</i> and experimental approaches

Considering the high inter-individual variation in humans and the well-controlled conditions in mice, our results suggest that mice, despite the identified limitations, most likely represent a suitable model for studying specific processes, such as stress responses, in the context of tobacco smoke exposure and its impact on the microbiota.

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Publication Details

Journal
Tobacco Induced Diseases
Published
2025-09-17
DOI
https://doi.org/10.18332/tid/208251
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Mouse model validity for studying the impact of tobacco smoke on the human gut microbiota assessed via in silico and experimental approaches

Corinna Bang, John F. Baines, Susanne Krauss‐Etschmann, Jan Hartmann et al.
Tobacco Induced Diseases
Gut microbiota and health
article

Mouse model validity for studying the impact of tobacco smoke on the human gut microbiota assessed via in silico and experimental approaches

Corinna Bang, John F. Baines, Susanne Krauss‐Etschmann, Jan Hartmann, Robert Häsler, Irene Victoria Bermúdez-Pérez sup sup, Juliana Meißner sup sup
article en

Abstract

Considering the high inter-individual variation in humans and the well-controlled conditions in mice, our results suggest that mice, despite the identified limitations, most likely represent a suitable model for studying specific processes, such as stress responses, in the context of tobacco smoke exposure and its impact on the microbiota.

Tobacco Induced DiseasesVol. 23(September)
Christian-Albrechts-Universität zu Kiel (DE), University Hospital Schleswig-Holstein (DE), Research Center Borstel - Leibniz Lung Center (DE), German Center for Lung Research (DE), Max Planck Institute for Evolutionary Biology (DE), University of Lübeck (DE)
Openalex Percentile: Top 78%
Gut microbiota and health
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