Development of a fully paper-based device for quantitative detection of digoxin at the point of care

We are the first to integrate H<sub>2</sub>O<sub>2</sub> degradation and gold nanorod (GNR) etching on paper with the lateral-flow immunoassay (LFA) in a 3D-printed device to achieve semi-quantitative results for therapeutic drug monitoring of digoxin by correlating different color outputs to different digoxin concentrations.

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Publication Details

Journal
The Analyst
Published
2025-01-01
DOI
https://doi.org/10.1039/d5an00800j
Primary Topic
Analytical Methods in Pharmaceuticals
Type
article
Field-Weighted Citation Impact
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Development of a fully paper-based device for quantitative detection of digoxin at the point of care

Daniel T. Kamei, Jiakun Lu, Kyle Chen, Jasmine Thanh Trinh et al.
The Analyst
Analytical Methods in Pharmaceuticals
article

Development of a fully paper-based device for quantitative detection of digoxin at the point of care

Daniel T. Kamei, Jiakun Lu, Kyle Chen, Jasmine Thanh Trinh, Audrey T. Sogata, Rika Nicole L Canlas
article en

Abstract

We are the first to integrate H<sub>2</sub>O<sub>2</sub> degradation and gold nanorod (GNR) etching on paper with the lateral-flow immunoassay (LFA) in a 3D-printed device to achieve semi-quantitative results for therapeutic drug monitoring of digoxin by correlating different color outputs to different digoxin concentrations.

The AnalystVol. 150(20)
University of California, Los Angeles (US)
Openalex Percentile: Top 72%
Analytical Methods in Pharmaceuticals
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