Erythroid Atypical Chemokine Receptor 1 Deficiency Aggravates Immune-Mediated Kidney Disease
Our data demonstrates that erythroid-specific ACKR1 deficiency led to an increased infiltration of the kidney by macrophages with an altered profibrotic phenotype in nephrotoxic serum nephritis, resulting in aggravated kidney disease.
Authors
- Maryna Samus (ORCID: https://orcid.org/0000-0002-5397-2183)
- Maria H. Ulvmar (ORCID: https://orcid.org/0000-0002-9050-0978)
- Antal Rot (ORCID: https://orcid.org/0000-0002-9730-6166)
- Theophilus Umeizudike (ORCID: https://orcid.org/0000-0002-0514-0972)
- Thomas Kroneis (ORCID: https://orcid.org/0000-0002-4761-9340)
- Igor Novitzky‐Basso (ORCID: https://orcid.org/0000-0003-3748-3117)
- Dagmar Kratky (ORCID: https://orcid.org/0000-0003-1357-7573)
- Katharina Artinger (ORCID: https://orcid.org/0000-0002-5677-3171)
- Konstantin A. Klötzer (ORCID: https://orcid.org/0009-0005-5022-2706)
- Andrea Bacon (ORCID: https://orcid.org/0000-0003-2688-8952)
- Agnes A. Mooslechner (ORCID: https://orcid.org/0000-0002-3266-3293)
- Alexander H. Kirsch (ORCID: https://orcid.org/0000-0001-6711-7834)
- Julia Gutjahr (ORCID: https://orcid.org/0000-0002-9193-8402)
- Nathaly Anto-Michel
- Corinna Schabhüttl (ORCID: https://orcid.org/0000-0002-1361-4015)
- Marion J. Pollheimer
- Stefan Wernitznig (ORCID: https://orcid.org/0000-0002-8547-5456)
- Elin Hub
- Kathrin Eller (ORCID: https://orcid.org/0000-0002-6214-5008)
- Philipp Eller (ORCID: https://orcid.org/0000-0001-5537-3646)
- Alexander R. Rosenkranz (ORCID: https://orcid.org/0000-0003-4838-2944)
- Daniel Leitinger
Institutions
- Uppsala University (SE)
- Queen Mary University of London (GB)
- University of Toronto (CA)
- Medical University of Graz (AT)
- Lagos University Teaching Hospital (NG)
- Princess Margaret Cancer Centre (CA)
- BioTechMed-Graz (AT)
- Lagos State University Teaching Hospital (NG)
- Biotechnology Institute Thurgau (CH)
- William Harvey Research Institute (GB)
- University of Birmingham (GB)
Publication Details
- Journal
- Journal of the American Society of Nephrology
- Published
- 2025-09-17
- DOI
- https://doi.org/10.1681/asn.0000000878
- Primary Topic
- Erythrocyte Function and Pathophysiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00