Microbial and Host Inflammatory Factors Induce Permeability and Activate Cytokine Production by Human Glomerular Microvascular Endothelial Cells
Lipopolysaccharide, interleukin-1β, and tumor necrosis factor-α induce glomerular microvascular endothelial cell permeability and production of IL-6 and IL-8, suggesting that glomerular endothelial activation may contribute to sepsis-related acute kidney injury.
Authors
- Michael P. Bokoch (ORCID: https://orcid.org/0000-0003-1387-9547)
- Judith Hellman (ORCID: https://orcid.org/0000-0003-2278-6625)
- Cindy Zhuang
- Kyle Tsutsui
- Fengyun Xu
Institutions
- University of California, San Francisco (US)
- SUNY Upstate Medical University (US)
Publication Details
- Journal
- Shock
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1097/shk.0000000000002702
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Friedreich's Ataxia Research Alliance
- Foundation for Anesthesia Education and Research
- University of California, San Francisco