Clinical evaluation of [18F]fluoro-2-deoxy-d-glucose positron emission tomography-magnetic resonance imaging ([18F]FDG PET-MRI) and [18F]FDG PET-computed tomography ([18F]FDG PET-CT) for lymph node assessment in head and neck squamous cell carcinoma
[18F]FDG PET-MRI/-CT demonstrate high accuracy in identifying malignant and benign lymph nodes. [18F]FDG PET-MRI shows slightly higher accuracy for suspicious lymph nodes, although diagnostic challenges remain. Advancements in imaging techniques and disease-specific tracers may improve lymph node evaluation in HNSCC, warranting prospective clinical trials to ultimately reduce reliance on pathological confirmation and minimise diagnostic delays.
Authors
- Roelf Valkema
- José A. Hardillo (ORCID: https://orcid.org/0000-0001-5580-5613)
- Sophie E. M. Veldhuijzen van Zanten (ORCID: https://orcid.org/0000-0002-3888-0977)
- Anke W. van der Eerden (ORCID: https://orcid.org/0000-0002-9182-9089)
- Anita A. Harteveld (ORCID: https://orcid.org/0000-0002-3379-0710)
- Tjeerd J. de Jong (ORCID: https://orcid.org/0000-0003-2677-316X)
- Ilanah J. Pruis (ORCID: https://orcid.org/0009-0000-8427-9755)
- H. Weber
- E Droogers
- C E M Kromkamp
Institutions
- Erasmus MC (NL)
- Erasmus MC Cancer Institute (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Clinical Radiology
- Published
- 2025-09-17
- DOI
- https://doi.org/10.1016/j.crad.2025.107095
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00