Biomechanical analysis of mandibular cartilage defect regeneration after implantation of human umbilical cord mesenchymal stem cells and a platelet rich fibrin scaffold: an experimental animal study
The implantation of hUCMSC results in a high compression and tensile strength of the regenerated defect. The implantation of hUCMSC or hUCMSC seeded on a PRF scaffold is a novel method for mandible cartilage regeneration, and they showed better biomechanics in shear strength and elastic modulus.
Authors
- Tengku Natasha Eleena binti Tengku Ahmad Noor (ORCID: https://orcid.org/0009-0005-4833-2738)
- Surya Atmajaya
- Andra Rizqiawan (ORCID: https://orcid.org/0000-0001-5306-7338)
- Olivia Jennifer Gunardi
- Ni Putu Mira Sumarta (ORCID: https://orcid.org/0000-0003-2192-1098)
- Coen Pramono Danudiningrat (ORCID: https://orcid.org/0000-0001-5971-919X)
Institutions
- Universitas Airlangga (ID)
- Sarawak General Hospital (MY)
Publication Details
- Journal
- Journal of Oral Biology and Craniofacial Research
- Published
- 2025-09-17
- DOI
- https://doi.org/10.1016/j.jobcr.2025.09.009
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitas Airlangga