Calculated Excess-Triglyceride Based on the Friedewald Formula is a Possible Surrogate Marker for the Production of Large Very-Low Density Lipoprotein, A Post-Hoc Analysis of the PROUD48 Study
The behavior of Ex-TG appears consistent with previous kinetic studies showing that omega-3FAs primarily suppress VLDL1 production, whereas fibrates promote TG removal, suggesting that Ex-TG serves as a surrogate marker for VLDL1 overproduction.
Authors
- Shinya Hiramitsu
- Mizuho Okada
- Ichiro Sakuma (ORCID: https://orcid.org/0000-0002-3863-0492)
- Yasutaka Takeda (ORCID: https://orcid.org/0000-0002-2129-8657)
- Tsutomu Hirano (ORCID: https://orcid.org/0000-0003-1859-0005)
- Shinichiro Ueda
- Masaru Sakurai (ORCID: https://orcid.org/0000-0002-4929-3225)
Institutions
- Kanazawa Medical University (JP)
- Sapporo Science Center (JP)
- Ebina General Hospital (JP)
- University of the Ryukyus University Hospital (JP)
Publication Details
- Journal
- Journal of Atherosclerosis and Thrombosis
- Published
- 2025-09-17
- DOI
- https://doi.org/10.5551/jat.65870
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00