An Emerging Pediatric CNS Tumor: Imaging Evaluation of <i>H3K27M</i> and <i>BRAF V600E</i> Comutated Midline Tumors
DMGs harboring both <i>H3K27M</i> and <i>BRAFV600E</i> mutations may represent a distinct subtype, with radiologic, histopathologic, and molecular features that appear different from those of non-MAPK-altered H3K27M DMGs.
Authors
- Tina Young Poussaint (ORCID: https://orcid.org/0000-0002-0814-0791)
- Sanda Alexandrescu (ORCID: https://orcid.org/0000-0001-9246-4184)
- Loai J. A. Aker (ORCID: https://orcid.org/0000-0001-6344-0984)
- Katie Pricola Fehnel (ORCID: https://orcid.org/0000-0001-9701-0931)
- Sridhar Vajapeyam (ORCID: https://orcid.org/0000-0002-1782-1919)
- Cesar Alves (ORCID: https://orcid.org/0000-0001-5877-9086)
- Hart G.W. Lidov (ORCID: https://orcid.org/0000-0002-1839-7603)
- Lissa Catherine Baird (ORCID: https://orcid.org/0000-0001-7996-1020)
- Kee Kiat Yeo (ORCID: https://orcid.org/0000-0003-0713-6384)
- Susan Chi (ORCID: https://orcid.org/0000-0001-7753-878X)
- Vanessa Rameh (ORCID: https://orcid.org/0000-0002-6007-7216)
- Karen D. Wright (ORCID: https://orcid.org/0000-0002-9578-1545)
- Alireza Ziaei
Institutions
- Boston Children's Hospital (US)
- Boston Children's Museum (US)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
- Mass General Brigham (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-09-17
- DOI
- https://doi.org/10.3174/ajnr.a9006
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00