From Diagnosis to Treatment: A Generative Adversarial Network Framework for Personalized Drug Discovery in Oncology

Cancer remains a leading cause of mortality worldwide. Personalized medicine offers a promising approach by tailoring care scheme to single diligent founded on their specific tumor symptomatic. This study explores the potential of generative adversarial networks (GANs) to accelerate personalized drug discovery in oncology. Identifying effective and safe cancer drugs is a time-consuming and expensive process. Traditional methods often rely on trial-and-error approaches with limited success rates. GANs leverage deep learning to generate new data resembling real-world examples, as algorithm with two competing neuronal networks: an apparatus and a differentiator. The apparatus makes novel data resembling real data, while the differentiator attempts to separate between actual and fake data. This adversarial training process allows GANs to learn complex relationships within data. This research proposes a novel GAN-based framework for personalized drug discovery in oncology. Here's a breakdown of the key components: Patient-Specific Tumor Data Integration: The framework integrates various patient-specific data sources, including genomic profiles, molecular characteristics, and treatment history.

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Publication Details

Journal
International Transactions in Mathematical Sciences and Computer
Published
2025-01-01
DOI
https://doi.org/10.58517/itmsc.2025.18201
Primary Topic
Computational Drug Discovery Methods
Type
article
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article

From Diagnosis to Treatment: A Generative Adversarial Network Framework for Personalized Drug Discovery in Oncology

Abhay Bhatia, Rajeev Kumar, Golnoosh Manteghi
International Transactions in Mathematical Sciences and Computer
Computational Drug Discovery Methods
article

From Diagnosis to Treatment: A Generative Adversarial Network Framework for Personalized Drug Discovery in Oncology

Abhay Bhatia, Rajeev Kumar, Golnoosh Manteghi
article en

Abstract

Cancer remains a leading cause of mortality worldwide. Personalized medicine offers a promising approach by tailoring care scheme to single diligent founded on their specific tumor symptomatic. This study explores the potential of generative adversarial networks (GANs) to accelerate personalized drug discovery in oncology. Identifying effective and safe cancer drugs is a time-consuming and expensive process. Traditional methods often rely on trial-and-error approaches with limited success rates. GANs leverage deep learning to generate new data resembling real-world examples, as algorithm with two competing neuronal networks: an apparatus and a differentiator. The apparatus makes novel data resembling real data, while the differentiator attempts to separate between actual and fake data. This adversarial training process allows GANs to learn complex relationships within data. This research proposes a novel GAN-based framework for personalized drug discovery in oncology. Here's a breakdown of the key components: Patient-Specific Tumor Data Integration: The framework integrates various patient-specific data sources, including genomic profiles, molecular characteristics, and treatment history.

International Transactions in Mathematical Sciences and ComputerVol. 18(02)
Openalex Percentile: Top 74%
Computational Drug Discovery Methods
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From Diagnosis to Treatment: A Generative Adversarial Network Framework for Personalized Drug Discovery in Oncology — Abhay Bhatia, Rajeev Kumar, et al. · International Transactions in Mathematical Sciences and Computer (2025) | TGRS Research Map | TGRS