From Diagnosis to Treatment: A Generative Adversarial Network Framework for Personalized Drug Discovery in Oncology
Cancer remains a leading cause of mortality worldwide. Personalized medicine offers a promising approach by tailoring care scheme to single diligent founded on their specific tumor symptomatic. This study explores the potential of generative adversarial networks (GANs) to accelerate personalized drug discovery in oncology. Identifying effective and safe cancer drugs is a time-consuming and expensive process. Traditional methods often rely on trial-and-error approaches with limited success rates. GANs leverage deep learning to generate new data resembling real-world examples, as algorithm with two competing neuronal networks: an apparatus and a differentiator. The apparatus makes novel data resembling real data, while the differentiator attempts to separate between actual and fake data. This adversarial training process allows GANs to learn complex relationships within data. This research proposes a novel GAN-based framework for personalized drug discovery in oncology. Here's a breakdown of the key components: Patient-Specific Tumor Data Integration: The framework integrates various patient-specific data sources, including genomic profiles, molecular characteristics, and treatment history.
Authors
- Abhay Bhatia (ORCID: https://orcid.org/0000-0001-7220-692X)
- Rajeev Kumar (ORCID: https://orcid.org/0000-0003-0233-6563)
- Golnoosh Manteghi
Publication Details
- Journal
- International Transactions in Mathematical Sciences and Computer
- Published
- 2025-01-01
- DOI
- https://doi.org/10.58517/itmsc.2025.18201
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00